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Microbe Breaks Genetic Code Rule

Researchers at UC Berkeley have uncovered a microbe, *Methanosarcina acetivorans*, that challenges a fundamental genetic principle by interpreting a "stop" codon as an instruction to insert an unusual amino acid and continue protein synthesis. This discovery reveals a surprising flexibility in the genetic code, overturning long-held beliefs about its rigidity and opening new avenues for understanding genetic disorders.

Microbe Breaks Genetic Code Rule
  • Researchers at the University of California, Berkeley, have identified a methane-producing microbe, *Methanosarcina acetivorans*, that challenges a fundamental genetic principle.
  • This microbe sometimes interprets a "stop" codon, which typically signals the end of protein synthesis, as an instruction to insert an unusual amino acid and continue building the protein.
  • As reported by Berkeley News, this flexible interpretation leads to the production of two distinct proteins from the same genetic sequence.
  • According to SSBCrack News, this discovery suggests that life can operate with a more flexible genetic code than previously understood, overturning a long-held belief in molecular biology.
  • The ambiguity in the genetic code allows *Methanosarcina acetivorans* to incorporate a rare amino acid called pyrrolysine, which is crucial for breaking down methylamine.
  • This finding has implications for understanding genetic disorders caused by premature stop codons, potentially opening avenues for new medical strategies.
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Editorial Process: This article was drafted using AI-assisted research and thoroughly reviewed by human editors for accuracy, tone, and clarity. All content undergoes human editorial review to ensure accuracy and neutrality.

Reviewed by: Norman Metanza

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