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New Gene Therapy Shows Promise for HIV Cure

A groundbreaking new gene therapy has successfully "functionally cured" monkeys infected with SHIV, offering a significant leap forward in the long-struggling fight against HIV. This innovative treatment works by delivering a gene that blocks the CCR5 receptor, a critical entry point for the virus, leading to sustained control for over a year after just a single injection.

New Gene Therapy Shows Promise for HIV Cure
  • Researchers have developed a novel gene therapy that has successfully "functionally cured" some monkeys infected with a simian-human immunodeficiency virus (SHIV).
  • According to Science, this therapy involves delivering a gene that produces an antibody designed to block the CCR5 receptor, which HIV uses to infect cells.
  • The gene therapy aims to prevent HIV from entering cells by targeting the CCR5 receptor, a critical entry point for the virus.
  • Six monkeys have demonstrated control over their SHIV infections for more than a year following a single injection of the gene therapy.
  • As reported by Aidsmap, this sustained control suggests a potential "functional cure," where the virus is suppressed without daily medication.
  • This breakthrough offers new momentum for gene-therapy approaches in the long-struggling effort to combat the AIDS virus.
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